Immobilized Biocatlyst Panels coming soon to a laboratory near you!

The team at FabricNano are preparing to launch a range of off-the-shelf immobilized enzymes. They will serve the biocatalysis needs of the pharmaceutical, fine chemicals and cosmetics industries. These Immobilized Biocatalysts are a product of our Immobilization Engineering^TM platform and were identified using our Predictive Immobilize Plate technology. 

These Immobilized Biocatalysts will:

• Accelerate development timelines and cost savings: drop-in off-the-shelf enzymes can save months to years of development time and save hundreds of thousands in development costs.
• Enable access to biocatalyst supply at scale: no need to worry about the assembly or scale of supply, we ensure QC’d immobilized enzymes arrive for both stirred tank and flow reactor processes.
• Deliver clear next-steps: where >10X performance is still required, we’re here to help you succeed using FabricNano’s proprietary Immobilization EngineeringTM platform.

Our first set of Immobilized Biocatalyst Panels will include: 

• Immobilized Ketone Reductases

• Immobilized Ene Reductases

• Immobilized Baeyer–Villiger Monooxygenases

• Immobilized Lipases 

Sounds interesting? Reach out to VP R&D Vishal Sanchania for co-development opportunities via email: vishal@fabricnano.com.

Schedule introductory call: Vishal Sanchania (VP R&D)

Enzymes are used ubiquitously across industry, ranging from all aspects of human and animal health and nutrition ¹, materials ², fuels ³, household cleaning ⁴ and more. The enzyme market is anticipated to double to ~$10Billion by 2031 ⁵. Several reports suggest ^5,6 that pharmaceutical, cosmetic and biotechnology sectors are major growth areas, along with the incumbent food and beverage industries which make up the majority. 

Applications of enzymes across these growth markets of pharmaceutical, cosmetics and biotechnology include: API intermediate synthesis, synthesis of active naturally occurring ingredients, and flavors and fragrances. Frequently, classical synthesis, raw material manufacturing and biocatalysis teams are racing to compete, co-develop and manufacture these respective chemistries in an economically viable way. Such rivalry and collaboration across business units and teams to maximize business outcomes is encouraging to see. However, biocatalytic routes are typically identified as more likely to be the preferred sustainable greener solution. 

Several sources suggest that we are continuing to witness a surge in biocatalysis endeavors across academia and also in industry to drive forward the green chemistry agenda ^7,9,10. However, personal insights from over a hundred discussions and more critical opinions from Novartis et al. suggest that the adoption of enzymatic green chemistry is not where it should be ⁸. Additional commentary from Prof. Roger Sheldon further bolsters the slow adoption ¹¹ and delivers credence to common themes such as the misconceptions surrounding costs of implementation and a lack of know-how regarding cutting edge technologies. It is also worth mentioning the current lack of funding in both industry and academia considering the promised outcomes expected from biocatalysis groups across the industry. 

Although the challenges the industry faces in adopting sustainable biocatalytic solutions are multi-level, they are surmountable. To overcome them we require technology and tools that can offer immediate value. Without such tools being available off-the-shelf as drop-in solutions, we risk seeing their adoption today – especially when considering the gaps that exist ^8,11.

FabricNano will be launching a range of Immobilized Biocatalyst panels and stand-alone solutions to enable customers to unlock new chemical transformations sooner and more efficiently whilst de-risking entire R&D programmes that would otherwise be at risk. 

The first wave of Immobilized Biocatalyst Panels will feature:

• Immobilized Ketone Reductases

• Immobilized Ene Reductases

• Immobilized Baeyer–Villiger Monooxygenases
• Immobilized Lipases 

Sounds interesting? Reach out to VP R&D Vishal Sanchania for co-development opportunities via email: vishal@fabricnano.com.